Indications and Usage

Altreno® (tretinoin) Lotion, 0.05% is indicated for the topical treatment of acne vulgaris in patients 9 years of age and older.

Important Safety Information

Altreno is for topical use only. Not for ophthalmic, oral, or intravaginal use.

Skin Irritation: Patients using Altreno may experience application site dryness, pain, erythema, irritation, and exfoliation.

Skin Irritation

Patients using Altreno may experience application site dryness, pain, erythema, irritation, and exfoliation. Depending upon the severity of these adverse reactions, instruct patients to use a moisturizer, reduce the frequency of the application of Altreno, or discontinue use. Avoid application of Altreno to eczematous or sunburned skin.

Ultraviolet Light and Environmental Exposure

Minimize unprotected exposure to ultraviolet light, including sunlight and sunlamps. Warn patients with frequent sun exposure and those with inherent sensitivity to sunlight to exercise caution. Use sunscreen and protective clothing over treated areas when exposure cannot be avoided.

Fish Allergies

Altreno contains soluble fish proteins. Use with caution in patients with known sensitivity or allergy to fish. Advise patients to contact their healthcare provider if they develop pruritus or urticaria.

Adverse Reactions

The most common adverse reactions in clinical trials were application site dryness (4%), pain (3%), erythema (2%), irritation (1%) and exfoliation (1%).

Nursing Women

It is not known whether topical administration of tretinoin could result in sufficient systemic absorption to produce detectable concentrations in human milk. The developmental health benefits of breastfeeding should be considered along with the mother’s clinical need for Altreno and any potential adverse effects on the breastfed child from Altreno.

To report suspected adverse reactions, contact Customer Service at 1-800-321-4576 or the FDA at 1-800-FDA-1088 or fda.gov/medwatch.

View full Prescribing Information

Skin Irritation

Patients using Altreno may experience application site dryness, pain, erythema, irritation, and exfoliation. Depending upon the severity of these adverse reactions, instruct patients to use a moisturizer, reduce the frequency of the application of Altreno, or discontinue use. Avoid application of Altreno to eczematous or sunburned skin.

Ultraviolet Light and
Environmental Exposure

Minimize unprotected exposure to ultraviolet light, including sunlight and sunlamps. Warn patients with frequent sun exposure and those with inherent sensitivity to sunlight to exercise caution. Use sunscreen and protective clothing over treated areas when exposure cannot be avoided.

Fish Allergies

Altreno contains soluble fish proteins. Use with caution in patients with known sensitivity or allergy to fish. Advise patients to contact their healthcare provider if they develop pruritus or urticaria.

Adverse Reactions

The most common adverse reactions in clinical trials were application site dryness (4%), pain (3%), erythema (2%), irritation (1%) and exfoliation (1%).

Nursing Women

It is not known whether topical administration of tretinoin could result in sufficient systemic absorption to produce detectable concentrations in human milk. The developmental health benefits of breastfeeding should be considered along with the mother’s clinical need for Altreno and any potential adverse effects on the breastfed child from Altreno.

To report suspected adverse reactions, contact Customer Service at 1-800-321-4576 or the FDA at 1-800-FDA-1088 or fda.gov/medwatch.

View Full Prescribing Information

Indications and Usage

Altreno® (tretinoin) Lotion, 0.05% is indicated for the topical treatment of acne vulgaris in patients 9 years of age and older.

Important Safety Information

Altreno is for topical use only. Not for ophthalmic, oral, or intravaginal use.

Skin Irritation: Patients using Altreno may experience application site dryness, pain, erythema, irritation, and exfoliation.

Altreno was named a top skincare product for 2020

 
 

An expert panel of dermatologists and editors reviewed hundreds of skincare products. Altreno was a winner.

As seen in:

  • Allure
  • Harper’s Bazaar
  • InStyle
  • Marie Claire
  • Total Beauty
  • Mind Body Green
  • New Beauty

“Altreno Lotion is a retinoid lotion formulation that has a nice vehicle, which we know is key because when a product has a nice vehicle, patients will use it, Altreno has a micronized, controlled-release vehicle, is hydrating, and spreads and absorbs quickly on the skin. Men and women both love it.”

According to Dr. Diane S. Berson, MD

“The latest advancement in vehicle formulation for tretinoin has brought prescribers the first topical lotion formulation of tretinoin 0.05% (Altreno, from Ortho Dermatologics). The novel lotion formulation incorporates a polymeric honeycomb matrix that helps provide a uniform distribution of both active and moisturizing/hydrating ingredients.”

Kircik LH et al (2019)

Kircik LH et al. Matrix revisited: Innovative approach for tretinoin. Journal of Drugs in Dermatology 2019;18(4 suppl 2):JO419

“The high levels of patient adherence [to once-daily tretinoin 0.05% lotion] (93% of patients were compliant with their application regimen) and greater patient preference (9 out of 10 patients reported to be satisfied with their treatment compared with previous acne therapy) are likely to translate to meaningful outcomes in the real-world clinical setting. Noteworthy is that patient preference to vehicle lotion was also greater than previous acne therapy.”

Tyring SK et al. (2018)

Tyring SK et al. Novel Tretinoin 0.05% Lotion for the Once-Daily Treatment of Moderate-to-Severe Acne Vulgaris: Assessment of Efficacy and Safety in Patients Aged 9 Years and Older. Journal of Drugs in Dermatology 2018;17(10):602-9

Patient Reviews

 

“I have had adult acne for years. Altreno has cleared out my acne almost completely. I am at a period where I don't have to wear makeup anymore. Highly recommend it.”

Review from WebMD

“I have been using Altreno for almost a month. I experienced acne that flared postpartum and this helped so much. My skin feels and looks so smooth.”

Review from WebMD

“I’m on week 3 so still early but so far not much is happening break out wise, my acne is calming down. You should definitely ask your derm about it, it’s all the buzz!”

Review from Reddit

“I've been using it [Altreno] every night for almost three weeks and I've had absolutely no redness and a very acceptable level of peeling (just the right amount to know it's working). I have post-menopausal acne primarily in the area of my chin and jawline.”

Review from WebMD

*This review is from an actual patient. Individual results may vary.

Altreno stimulates skin cell turnover
to treat your patients' acne.
 
 

Physician
Dispense

 
 
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Altreno

Indications and Usage

Altreno® (tretinoin) Lotion, 0.05% is indicated for the topical treatment of acne vulgaris in patients 9 years of age and older.

Important Safety Information

Altreno is for topical use only. Not for ophthalmic, oral, or intravaginal use.

Skin Irritation: Patients using Altreno may experience application site dryness, pain, erythema, irritation, and exfoliation.

Skin Irritation

Patients using Altreno may experience application site dryness, pain, erythema, irritation, and exfoliation. Depending upon the severity of these adverse reactions, instruct patients to use a moisturizer, reduce the frequency of the application of Altreno, or discontinue use. Avoid application of Altreno to eczematous or sunburned skin.

Ultraviolet Light and Environmental Exposure

Minimize unprotected exposure to ultraviolet light, including sunlight and sunlamps. Warn patients with frequent sun exposure and those with inherent sensitivity to sunlight to exercise caution. Use sunscreen and protective clothing over treated areas when exposure cannot be avoided.

Fish Allergies

Altreno contains soluble fish proteins. Use with caution in patients with known sensitivity or allergy to fish. Advise patients to contact their healthcare provider if they develop pruritus or urticaria.

Adverse Reactions

The most common adverse reactions in clinical trials were application site dryness (4%), pain (3%), erythema (2%), irritation (1%) and exfoliation (1%).

Nursing Women

It is not known whether topical administration of tretinoin could result in sufficient systemic absorption to produce detectable concentrations in human milk. The developmental health benefits of breastfeeding should be considered along with the mother’s clinical need for Altreno and any potential adverse effects on the breastfed child from Altreno.

To report suspected adverse reactions, contact Customer Service at 1-800-321-4576 or the FDA at 1-800-FDA-1088 or fda.gov/medwatch.

View full Prescribing Information

 
Altreno

How Do I Get Altreno?

Altreno is a powerful Rx product, which means it requires a prescription. We can help you get in touch with a healthcare provider in two easy ways:

1. Online consultation
2. In-person visit

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