ALTRENO lotion is the first and only acne treatment that provides the proven efficacy of tretinoin in a hydrating lotion.1,2

Ingredients Proven to Hydrate the Skin2-5

  • Sodium hyaluronate
  • Glycerin
  • Soluble collagen

Results from a customer perception study of patients using only the lotion vehicle1

87%

Strongly or somewhat agreed that

  • The lotion vehicle absorbed quickly1
  • The lotion vehicle had a lightweight feeling after application1
  • The lotion vehicle provided lightweight hydration1

In this self-assessment, 15 subjects aged 35 to 65 years applied the lotion vehicle to the left side of their face, while leaving the other side untreated.1

Woman looking forward

SODIUM HYALURONATE IS THE SODIUM SALT OF HYALURONIC ACID AND IS VALUED AS AN excellent HYDRATING INGREDIENT IN TOPICAL SKIN CARE PRODUCTS.3

INDICATION

ALTRENO™ (tretinoin) lotion, 0.05% is indicated for the topical treatment of acne vulgaris in patients 9 years of age and older.

IMPORTANT SAFETY INFORMATION

ALTRENO is for topical use only. Not for ophthalmic, oral, or intravaginal use.

Skin Irritation: Patients using ALTRENO may experience application site dryness, pain, erythema, irritation, and exfoliation. Depending upon the severity of these adverse reactions, instruct patients to use a moisturizer, reduce the frequency of the application of ALTRENO, or discontinue use. Avoid application of ALTRENO to eczematous or sunburned skin.

Ultraviolet Light and Environmental Exposure: Minimize unprotected exposure to ultraviolet light, including sunlight and sunlamps. Warn patients with frequent sun exposure and those with inherent sensitivity to sunlight to exercise caution. Use sunscreen and protective clothing over treated areas when exposure cannot be avoided.

Fish Allergies: ALTRENO contains soluble fish proteins. Use with caution in patients with known sensitivity or allergy to fish. Advise patients to contact their healthcare provider if they develop pruritus or urticaria.

Adverse Reactions: The most common adverse reactions in clinical trials were application site dryness (4%), pain (3%), erythema (2%), irritation (1%) and exfoliation (1%).

Nursing Women: It is not known whether topical administration of tretinoin could result in sufficient systemic absorption to produce detectable concentrations in human milk. The developmental health benefits of breastfeeding should be considered along with the mother’s clinical need for ALTRENO and any potential adverse effects on the breastfed child from ALTRENO.

To report SUSPECTED ADVERSE REACTIONS, contact Customer Service at 1-800-321-4576 or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please click here for full Prescribing Information.

References:

  • Data on file. Ortho Dermatologics.
  • ALTRENO lotion [package insert]. Bridgewater, NJ: Ortho Dermatologics.
  • Wang Y, Viennet C, Jeudy A, Fanian F, He L, Humbert P. Assessment of the efficacy of a new complex antisensitive skin cream. J Cosmet Dermatol. 2018;17(6):1101-1107.
  • Dermatologists’ top tips for relieving dry skin. American Academy of Dermatology website. https://www.aad.org/public/skin-hair-nails/skin-care/dry-skin. Accessed January 3, 2019.
  • Morganti P, Randazzo SD, Cardillo A. Role of insoluble and soluble collagen as skin moisturizer. J Appl Cosmetol. 1986;4:141-152.

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